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From Biotech to Wellness: The 2025 Skincare Revolution

Biotech-driven innovation is reshaping skincare, with brands turning to sustainable, green-chemistry-powered actives

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Released By Provital LLC

Skincare is evolving toward biotech-driven innovation, with sustainable, clinically validated platforms such as the Triplobiome™ technology setting new standards for both efficacy and responsibility. At the same time, the category is embracing holistic wellness, longevity, and personalization through next-gen delivery systems. Consumers are also demanding proof—85% want more scientific evidence and 77% expect trial results on packaging (Mintel®).

Biotech-driven innovation is reshaping skincare, with brands turning to sustainable, green-chemistry-powered actives that deliver high performance and differentiate premium offerings with clinical validation remaining essential to build trust and adoption.

Through Triplobiomeâ„¢ Technology, Provital has built a library of over 100 endophytes, opening broad opportunities for new actives and reinforcing its leadership in sustainable innovation. Endophytes are symbiotic microorganisms inside plants that boost growth, pathogen resistance, and stress tolerance while producing bioactive compounds useful for cosmetics.

In addition, Provital has also created the first ecosystem ingredients with Triplobiomeâ„¢ Technology.

Shiloxomeâ„¢ – Protecting From Within

The Cork Oak (Quercus suber) is a tree known for its longevity, as it can live for centuries. Such survival is achieved thanks to adaptive systems like its insulating bark. Provital isolated the endophytic yeast Kwoniella mangroviensis from the inside of this bark.

Multi-ome Skin Protection

We move beyond barrier care to deliver anti-pollution protection and both preventative and corrective well-aging benefits. Exposomic studies reveal Shiloxomeâ„¢ prevents ROS formation while preserving microbiome diversity. Lipidomic analysis shows it fortifies the lipidome by reducing pollution-induced lipid peroxidation. Transcriptomic profiling demonstrates activation of key dermal pathways essential for healthy aging.

Pureblomeâ„¢ – Protecting From Within

Provital isolated the highly bioactive endophytic bacteria Bacillus velezensis from the inside of the leaf’s tissue of the agroecological hyssop (Hyssopus officinalis) from our cherished local supplier, Parc de les Olors.

Triple Efficacy

Pureblomeâ„¢ is a post-biotic active that harmonizes the skin of ever-blooming women, delivering Triple Efficacy with dual action. It revitalizes fibroblasts to promote dermal regeneration, rebalances sebocytes for refined skin purity, and combats inflammaging to achieve total evenness. By improving acne and inflammation while supporting overall skin regeneration, Pureblomeâ„¢ helps prevent visible signs of aging and effectively purifies the skin.

To learn more about these high powered green-chemistry-powered actives, click here.

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