LipoTrue is constantly working to meet the needs of the cosmetic market, with the goal to develop innovativeactive ingredients that deliver the best results. That is why LipoTrue has launched two novel active ingredients, a plant-based protein targeting dermochronology and a botanical ingredient to regulate sebum and reduce pores.

We have always been told that skin has memory just like trees. If we listen carefully, we can hear them whispering our story. Trees need sunlight for growth, and their history can be read in their rings. In them they record not only age (dendrochronology), but also each season and climate experience (wet, hot, early frosts, sunlight, etc). But do we know a person's history from their skin? Like trees, humans need sunlight to be healthy, but an excess of UV exposure is also recorded in our skin in premature and deep wrinkles and leathery texture.

We want the years to go by but not be reflected in the skin. Therefore, LipoTrue has developed Timlog™, a plant-derived human TIMP-2 (tissue inhibitor of metalloproteinases) transiently expressed through the Wild plants as a biofactory technology. TIMP-2 is an inhibitor of all MMPs (specifically of MMP-2). Additionally, it increases fibromodulin which has an important role in organizing the ECM by binding to collagen, resulting in delay of fibril formation and the formation of thinner fibers. Timlog™acts as a guardian for skin’s dermochronology, repairing dermal solar scars redefining the past.

On the other hand, sebum hydrates and protects the skin against UV radiation and infections, transports fat-soluble antioxidants, locks skin moisture and maintains skin pH. But what happens when there is an overproduction? LipoTrue presents Echioseb™, an ingredient obtained from Echinacea purpurea, and the stem cells from Rhodiola rosea from Greenology technology.
 
Adaptability is a critical quality for plant survival in hostile conditions and Echinacea purpurea is a drought tolerant plant, having evolved mechanisms to reduce water loss (e.g. partial opening of stomata) and increase water uptake, allowing it to survive during fluctuations in rainfall in the North American prairies.

Additionally, there are plants that not only adapt to hostile conditions but also help other organisms cope with stressors to normalize metabolic functions. Rhodiola rosea is an adaptogen was known by the Vikings for enhancing physical endurance and mental alertness and was highly evaluated by Chinese emperors who sent expeditions to Siberia.

Echioseb™function is to adapt and allow the skin to normalize sebum content and release, pore size, elasticity and hydration by regulating the sebum biosynthetic pathway following the steps of retinoids. It is the adaptogenic sebum controller that customizes its efficacy by adapting to the different needs of combination and oily skin.