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The launch marks a new skincare segment of advanced hydration and firming solutions designed specifically for improving the appearance of aging.
September 22, 2025
By: Lianna Albrizio
Associate Editor
Galderma-owned Cetaphil – the dermatologist-recommended brand trusted by millions with sensitive skin – is championing the longevity trend with the launch of its new Skin Activator Hydrating & Firming line.
The launch marks a new skincare segment of advanced hydration and firming solutions designed specifically for improving the appearance of aging, thinning and fragile skin. As people age, surface skin cells stop performing at the same level, or “go to sleep,” causing fine lines, dehydration, and looser skin, in turn leading to skin looking and feeling less firm and more fragile.
“This launch signals a turning point in how we approach skin longevity,” said Alan D. Widgerow, chief scientific officer, Galderma. “It’s more fundamental than wrinkles or loss of firmness, it’s about preserving surface skin health at the cellular level. As skin undergoes changes with age, it demands more precise, science-driven support. This insight fueled the development of our Skin Activator Hydrating & Firming line: a dermatologist-developed routine designed to strengthen, revitalize and transform skin’s appearance.”
Skin Activator technology serves as a “wake-up call” to sleeping surface skin cells, per marketers. The unique complex is powered by encapsulated CICA to help restore the skin’s moisture barrier to visibly plump and firm skin as well as microdosed mandelic acid to increase surface skin cell turnover to visibly reduce dull, uneven skin.
In clinical trials, the Skin Activator Hydrating & Firming Lotion showed to be effective in improving the appearance of skin crepiness and smooth skin’s texture in one week. It was also proven to hydrate for firmer-looking skin in just four weeks. Moreover, when patients were asked about their experiences, 88% of Skin Activator Hydrating & Firming Cream users said their skin looked less crepey in two days, and 87% said their skin appeared more youthful after one week.
In developing the Skin Activator Hydrating & Firming Line, Galderma partnered with a medical advisory board of leading dermatologists.
According to Board Certified Dermatologist Dr. Glynis Ablon, associate clinical professor at the University of California, they took on one of the biggest underlying causes of visible aging: surface skin health and cell senescence. By targeting these so-called “zombie cells,” they’re helping to support skin renewal in a science-backed way.
“It’s been incredibly rewarding to help bring that kind of innovation to a skincare routine patients can use all over, every day,” he noted.
Fragrance-free, non-comedogenic and hypoallergenic, the Skin Activator Hydrating & Firming line embraces the trending notion of “skinification,” or using facial care-inspired ingredients to address full-body skincare needs.
Products within the newly launched Skin Activator Hydrating & Firming Line include:Cetaphil Hydrating & Firming Cream for Neck, Chest, and Face;Cetaphil Hydrating & Firming Cream for Body; andCetaphil Hydrating & Firming Lotion.
Cetaphil partnered with actress, director and advocate, Mariska Hargitay, known for her strength, compassion and authenticity, to represent a powerful voice in embracing beauty at all life stages. As the face of the campaign, she will help share a message of empowerment and reinvention – giving women the tools to reawaken both their skin’s look and their aspirations. Hargitay’s partnership will span a robust marketing effort, inclusive of PR, advertising, in-store, retailer e-commerce and social.
The Hydrating & Firming Line is now available for purchase in the US. Galderma is working to bring this new innovation to other international markets where Cetaphil is already available.
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