Agetect is a new novel ingredient made from Longan seeds. Longan is a fruit in Southeast Asia and Central America. The ingredient is manufactured by Katakura Chikkarin, a Japanese company, and represented in North America by Independent Chemical Corporation.

According to the company, the enzymes most active in the matrix, the metalloproteases or MMPs are most affected by aging. The balance between the MMPs, such as matrix collagenase, elastase, geratinase, hyaluronidase and others and their inhibitors is disrupted. In addition, photoaging due to the effect of ultraviolet radiation produces characteristic changes in extracellular matrices, such as a decrease in collagen and a hardening of elastin. Biological changes in extracellular matrix components observed in photoaging are induced by Reactive Oxygen Species. Reactive Oxygen Species stimulate MMP enzyme activity resulting in a decrease of the extracellular matrix. This leads to modification of the mechanical properties of the skin and significantly contributes to wrinkle formation.

Agetect has proven collagenase and hyaluronidase inhibition activity. As Agetect controls MMP activity, it is suggested that Agetect provides a great benefit when used in cosmetic products such as anti-wrinkle agents.

More info: www.independentchemical.com