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The founder’s inspirational trip to Tokyo inspired the hybrid gel-oil serum, which visibly firms, strengthens and smooths skin while proactively delaying signs of aging.
August 21, 2025
By: Lianna Albrizio
Associate Editor
Japanese skincare brand Tatcha is tapping into the vitality of Okinawa, a Japanese island where residents are said to live longer, in its new longevity serum.
Seven years in the making, Tatcha’s Longevity Serum was inspired by Tatcha Founder Vicky Tsai’s trip there. She said she encountered the healing philosophy of nuchi-gusui (“life medicine” in English) — wild, nutrient-rich herbs and plants used for generations to protect and restore well-being. These ingredients, she said, helped heal her skin and spirit.
Tatcha’s Longevity Serum contains the Okinawa Cellescence Complex. Crafted at the Tatcha Institute in Tokyo, The Longevity Serum is a hybrid gel-oil serum that visibly firms, strengthens and smooths skin, while proactively delaying signs of aging by addressing cellular senescence — the buildup of so-called “zombie” cells that drive chronic inflammation (inflammaging). The Okinawa Cellescence Complex is a proprietary blend of time-honored botanicals including shikuwasa lime for tone evening, noni juice for barrier strengthening, and shell ginger for exfoliation. Together these ingredients work to reduce senescent cells and prevent future accumulation, extending skin’s healthy, youthful state.
Bio-Active Lipids target oxidative stress to support collagen and elastin for a visibly firmer, smoother complexion. Its Pro-AHA prebiotic activates natural exfoliating acids to promote cell turnover and support the microbiome.
Per in vitro testing stress-induced senescent cell biomarkers, 55% saw a reduction in aging senescent cell markers; 100% of users showed firmer, smoother skin after one week; and 25% saw an improvement in visible firmness after four weeks.
Tatcha’s Longevity Serum retails for $80 at Tatcha.com and Sephora.com.
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